IN-HOSPITAL OUTCOMES OF FEMORAL-POPLITEAL BYPASS SURGERY ABOVE AND BELOW THE KNEE JOINT GAP USING THE “KEMANGIOPROTEZ” VASCULAR XENOGRAFT

Highlights

Reconstructive interventions on the arteries of the lower extremities remain an extremely common type of treatment for arteriosclerosis obliterans. Research in this area will help determine the indications for implantation of understudied but effective vascular xenografts, which have a number of significant advantages over other types of prostheses and surgical treatment methods.

Abstract

Aim. To analyze in-hospital outcomes of femoropopliteal bypass grafting above and below the knee joint gap using the “KemAngioprotez” vascular xenograft.

Methods. The retrospective study included 115 patients undergoing infrainguinal arterial reconstructions (femoral segment) using the “KemAngioprotez” epoxy-treated vascular xenograft (CJSC NeoKor, Kemerovo) for chronic arterial occlusive disease of the lower extremities from 2012 to 2022.

Results. 7 patients (6.1%) suffered thrombosis in vascular xenograft, including 2 cases (20%) with the point of formation of the distal anastomosis below the knee joint gap, 5 cases (4.8%) – above the gap (p = 0.113). Of the analyzed predictors of 30-day thrombosis and other complications in this period, the number of functioning arteries of the leg and the type of antiplatelet therapy were statistically significant. There were no fatal outcomes. 3 patients (2.6%) undergone repeated arterial reconstruction to restore peripheral blood flow. 2 patients (1.7%) with coronary artery disease and a history of myocardial infarction suffered perioperative myocardial infarction. 12 patients (10.4%) had lymphorrhea. 6 (5.2%) patients had postoperative wound diastasis; 2 (1.7%) patients had marginal necrosis.

Conclusion. In-hospital outcomes of infrainguinal revascularization of the lower extremities using the “KemAngioprotez” epoxy-treated vascular xenograft are comparable with bypass with autologous veins. This may be due to the satisfactory implantation properties of the vascular xenograft. Further multicenter prospective randomized studies are required to study the main limitation of the use of vascular prosthesis according to the literature – the tendency towards degeneration.

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