CHARACTERISTICS OF THE EPIDEMIC PROCESS OF HEALTHCARE-ASSOCIATED INFECTIONS IN CARDIAC SURGERY
https://doi.org/10.17802/2306-1278-2025-14-6S-273-290
Abstract
Highlights
- This analytical review aims to examine the features of the epidemic process of healthcare-associated infections in cardiac surgery.
- Based on the data described, risk-oriented technologies are considered an effective system for preventing infectious adverse events.
Abstract
The review is dedicated to a comprehensive analysis of the epidemic process of healthcare-associated infections in cardiac surgery. Despite the rapid development of high-tech and minimally invasive methods for treating circulatory system diseases, the problem of infectious complications after heart surgery remains extremely acute. Cardiac surgery patients present in severe condition, and the surgeries themselves carry a high risk of complications, characterized by significant prevalence, mortality, and colossal economic damage. The main forms of healthcare-associated infections, their pathogens, as well as risk factors and modern prevention approaches are described in detail. Priority is given to risk-oriented technologies as the most effective system for preventing adverse events in cardiac surgery.
About the Author
Evgeny E. Sadovnikov
Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”
Russian Federation
Russian Federation
PhD, Epidemiologist, Federal State Budgetary Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Kemerovo, Russian Federation
References
1. Healthcare in Russia. 2023: Statistical Compendium / Rosstat. – M., 2023. – 179 p.
2. Tsoi, E. R. Assessment of the Probability of Surgical Site Infections Development Depending on the NNIS Integral Indicator in Trauma and Surgical Patients / E. R. Tsoi, E. A. Garbaruk, S. A. Breger // Mechnikov Readings. April 24-25, 2019. – St. Petersburg, 2019. – P. 276–277.
3. Financial Impact of Deep Sternal Wound Infections After Coronary Surgery: A Microcosting Analysis / B. M. M. Orlandi, O. A. V. Mejia, E. M. Trindade [et al.] // Brazilian Journal of Cardiovascular Surgery. – 2023. – Vol. 38 (5): e20220261.
4. Li, H. Extensive analysis of risk factors associated with surgical site infections post-cardiothoracic open surgery / H. Li, X. Zheng, J. Gao // International Wound Journal. – 2024. – Vol. 21 (3): e14842.
5. Brusina, E. B. Risk Management of Healthcare-Associated Infections / E. B. Brusina, O. L. Barbarash // Medical Almanac. – 2015. – No. 5 (40). – P. 22–25.
6. Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level. – Geneva: World Health Organization, 2021. License: CC BY-NC-SA 3.0 IGO.
7. Nabiyeva, A. S. Risk Factors for Healthcare-Associated Infections in Pediatric Cardiac Surgery / A. S. Nabiyeva, B. I. Aslanov, A. V. Nokhrin // Public Health and Life Environment - ZNiSO. – 2022. – Vol. 30, No. 11. – P. 69–75.
8. Liu, Z. Clinical investigation of nosocomial infections in adult patients after cardiac surgery / Z. Liu, X. Zhang, Q. Zhai // Medicine (Baltimore). – 2021. – Vol. 100 (4): e24162.
9. Russkikh, A. A. Optimization of the Management System for the Epidemic Process of Healthcare-Associated Pneumonias in Intensive Care Units During the COVID-19 Pandemic / A. A. Russkikh, N. V. Lukyanenko // Sanitary Doctor. – 2025. – Vol. 22, No. 3(254). – P. 169–180.
10. Song, Y. Risk factors for ventilator-associated pneumonia after cardiac surgery with cardiopulmonary bypass / Y. Song, J. Gu, J. Yang // Asian Journal of Surgery. – 2024. – Vol. 47 (2). – P. 1279–1280.
11. Surgical Treatment of Sternal Osteomyelitis and Sternal Wound Infection Following Cardiac Surgery / A. A. Shevchenko, K. P. Topalov, N. G. Zhila [et al.] // Surgery. The Journal Named after N.I. Pirogov. – 2021. – No. 9. – P. 34–39.
12. Zukowska, A. Surgical Site Infection in Cardiac Surgery / A. Zukowska, M. Zukowski // Journal of Clinical Medicine. – 2022. – Vol. 11 (23): 6991.
13. Stepin, A. V. Modifiable Risk Factors and Modern Approaches to Prevention of Surgical Site Infection in Cardiac Surgery / A. V. Stepin // Clinical and Experimental Surgery. The Journal Named after Academician B.V. Petrovsky. – 2022. – Vol. 10, No. 2. – P. 126–133.
14. The association of intraoperative and early postoperative events with risk of pneumonia following cardiac surgery / N. M. Barnett, D. R. Liesman, R. J. Strobel [et al.] // The Journal of Thoracic and Cardiovascular Surgery. – 2023. – Vol. 168 (4). – P. 1144-1154.e3.
15. Healthcare-Associated Infections: Modern Doctrine of Prevention. Part 2. Basic Provisions / E. B. Brusina, L. P. Zuyeva, O. V. Kovalishina [et al.] // Epidemiology and Vaccinal Prevention. – 2018. No. 6. – P. 4–10.
16. Healthcare-Associated Infections: Current State of the Problem and Prospects / V. G. Akimkin, E. B. Brusina, N. I. Briko, A. V. Tutelyan // Bulletin of the Russian Academy of Medical Sciences. – 2024. – Vol. 79, No. 5. – P. 406–415.
17. Shmakova, M. A. Bacteria of the Genus Acinetobacter as Nosocomial Pathogens: Epidemiological Features / M. A. Shmakova // Fundamental and Clinical Medicine. – 2019. – Vol. 4, No. 1. – P. 66–72.
18. Global prevalence of nosocomial infection: A systematic review and meta-analysis / S. Raoofi, Pashazadeh Kan F., S. Rafiei [et al.] // PLoS ONE. – 2023. – Vol. 18 (1): e0274248.
19. Brusina, E. B. Healthcare-Associated Infections in Surgery: Trends and Prospects for Prevention / E. B. Brusina, O. V. Kovalishina, A. M. Tsigelnik // Epidemiology and Vaccinal Prevention. – 2017. No. 4. – P. 73–80.
20. Sergevnin, V. I. Frequency and Risk Factors of Purulent-Septic Infections in Adults After Various Types of Open Heart Surgery / V. I. Sergevnin, L. G. Kudryavtseva, A. I. Zolotukhina // Epidemiology and Vaccinal Prevention. – 2020. – No. 5. – P. 34–40.
21. State Report "On the State of Sanitary and Epidemiological Well-Being of the Population in the Russian Federation in 2023" [Electronic resource]. – URL: https://www.rospotrebnadzor.ru/documents/details.php?ELEMENT_ID=27779
22. Healthcare-Associated Infections. A Modern View on the Problem (Literature Review) / A. M. Morozov, A. D. Morozova, M. A. Belyak [et al.] // Bulletin of New Medical Technologies. – 2022. – Vol. 16, No. 4. – P. 107–116.
23. Akimkin, V. G. Optimization of the System of Measures to Combat and Prevent Healthcare-Associated Infections in the Russian Federation / V. G. Akimkin // Bulletin of VSHOUZ. – 2018. – No. 1 (11). – P. 17–26.
24. The first WHO global survey on infection prevention and control in health-care facilities / S. Tomczyk, A. Twyman, M. E. A. de Kraker [et al.] // The Lancet Infectious Diseases. – 2022. – Vol. 22. – P. 845–856.
25. Emerging Infections Program Hospital Prevalence Survey Team. Changes in Prevalence of Health Care-Associated Infections in U.S. Hospitals / S. S. Magill, E. O'Leary, S. J. Janelle [et al.] // New England Journal of Medicine. – 2018. – Vol. 379 (18). – P. 1732–1744.
26. Trends in health care-associated infections in acute care hospitals in Canada: an analysis of repeated point-prevalence surveys / R. Mitchell, G. Taylor, W. Rudnick [et al.] // CMAJ. – 2019. – Vol. 191: E981-E988.
27. Surveillance of health care-associated infections at national and facility levels: practical handbook [Electronic resource] / World Health Organization, 2024. – URL: https://www.who.int/publications/i/item/9789240101456
28. Ventilator-associated pneumonia: pathobiological heterogeneity and diagnostic challenges / F. Howroyd, C. Chacko, A. MacDuff [et al.] // Nature Communications. – 2024. – Vol. 15 (1): 6447.
29. Effect of oropharyngeal povidone-iodine preventive oral care on ventilator-associated pneumonia in severely brain-injured or cerebral hemorrhage patients: a multicenter, randomized controlled trial / P. Seguin, B. Laviolle, C. Dahyot-Fizelier [et al.] // Critical Care Medicine. – 2014. – Vol. 42. – P. 1–8.
30. Papazian, L. Ventilator-associated pneumonia in adults: a narrative review / L. Papazian, M. Klompas, C. E. Luyt // Intensive Care Medicine. – 2020. – Vol. 46. – P. 888–906.
31. Koulenti, D. Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study / D. Koulenti, E. Tsigou, J. Rello // European Journal of Clinical Microbiology & Infectious Diseases. – 2017. – Vol. 36. – P. 1999–2006.
32. A systematic review and meta-analysis of ventilator-associated pneumonia in adults in Asia: an analysis of national income level on incidence and etiology / A. Bonell, R. Azzarafiy, V. T. L. Huong [et al.] // Clinical Infectious Diseases. – 2019. – Vol. 68. – P. 511–518.
33. International Nosocomial Infection Control Consortium (INICC) report, data summary of 45 countries for 2013-2018, adult and pediatric units, device-associated module / V. D. Rosenthal, W. Dusznska, B. E. Ider [et al.] // American Journal of Infection Control. – 2021. – Vol. 49. – P. 1267–1274.
34. Prevalence, risk factors, and antimicrobial resistance of endemic healthcare-associated infections in Africa: a systematic review and meta-analysis / G. K. Bunduki, E. Masoamphambe, T. Fox [et al.] // BMC Infectious Diseases. – 2024. – Vol. 24. – P. 158.
35. Centers for Disease Control and Prevention. Current HAI progress report [Electronic resource]. – URL: https://www.cdc.gov/hai/data/portal/progress-report.html (accessed Jan. 20, 2021.)
36. Global report on infection prevention and control. 2024 [Electronic resource]. – URL: https://www.who.int/publications/i/item/9789240103986
37. Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis / R. Markwart, H. Saito, T. Harder [et al.] // Intensive Care Medicine. – 2020. – Vol. 46. – P. 1536–1551.
38. Prevalence of Central Line-Associated Bloodstream Infections (CLABSI) in Intensive Care and Medical-Surgical Units / H. Toor, S. Farr, P. Savla [et al.] // Cureus. – 2022. – Vol. 14 (3): e22809.
39. Modelling the annual NHS costs and outcomes attributable to healthcare-associated infections in England / J. F. Guest, T. Keating, D. Gould [et al.] // BMJ Open. – 2020. – Vol. 10 (1): e033367.
40. OECD Strategic Public Health Planning for infectious diseases model was used. OECD; 2023 [Electronic resource]. – URL: http://oecdpublichealthexplorer.org/amr-doc/
41. Issa, M. Hand hygiene practices for prevention of health care-associated infections associated with admitted infectious patients in the emergency department: a systematic review / M. Issa, S. S. Dunne, C. P. Dunne // Irish Journal of Medical Science. – 2023. – Vol. 192 (2). – P. 871–899.
42. Stewart, S. Impact of healthcare-associated infection on length of stay / S. Stewart, C. Robertson, J. Pan [et al.] // Journal of Hospital Infection. – 2021. – Vol. 114. – P. 23–31.
43. Improving the System for Prevention of Healthcare-Associated Infections and Combating Antibiotic Resistance Based on Optimizing the Interaction of Participants in the Diagnostic and Treatment Process / Y. E. Abramov, A. B. Timurziyeva, O. A. Orlova [et al.] // Public Health and Life Environment. – 2023. – No. 31 (8). – P. 88–97.
44. Naygovzina, N. B. Optimization of the System of Measures to Combat and Prevent Healthcare-Associated Infections in the Russian Federation / N. B. Naygovzina, A. Y. Popova, E. E. Biryukova // ORGZDRAV: News. Opinion. Training. Bulletin of VSHOUZ. – 2018. – Vol. 1, No. 11. – P. 17–26.
45. New Technologies in the Complex of Measures for Non-Specific Prevention of Healthcare-Associated Infections / O. A. Orlova, N. A. Yumtsunova, T. A. Semenenko [et al.] // Hygiene and Sanitation. – 2020. – No. 10. – P. 1055–1060.
46. Briko, N. I. Theoretical Generalizations in Epidemiology: From History to Modernity / N. I. Briko // Epidemiology and Vaccinal Prevention. – 2018. – Vol. 17, No. 5. P. 5–16.
47. Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update / M. S. Calderwood, D. J. Anderson, D. W. Bratzler [et al.] // Infection Control & Hospital Epidemiology. – 2023. – Vol. 44 (5). – P. 695–720.
48. Interdisciplinary Infection Prevention and Control Bundle in Neurosurgical Patients: Results of a Prospective Cohort Study / J. Koch, S. Saydan, F. Schwab [et al.] // Neurosurgery. – 2023. – Vol. 93 (4). – P. 835–846.
49. The effect of an infection control guideline on the incidence of ventilator-associated pneumonia in patients admitted to the intensive care units / A. Safavi, S. Molavynejad, M. Rashidi [et al.] // BMC Infectious Diseases. – 2023. – Vol. 23 (1). – P. 198.
50. Electronic Version of the Information Module of the Medical History in Surgical Pathology / M. G. Darina, K. N. Movchan, B. S. Artushin [et al.] // Scientific Notes of the Pavlov St. Petersburg State Medical University. – 2019. – Vol. 26, No. 2. – P. 41–46.
51. Chen, C. Enhancing Nosocomial Infection Control through the Implementation of High-Quality Nursing Practices / C. Chen, J. Liu // Alternative Therapies in Health and Medicine. – 2024. – Vol. 30 (8). – P. 300–305.
52. Provision of High-Tech Medical Care in "Cardiovascular Surgery" to Residents of the Subjects of the Russian Federation in 2021 / E. Z. Golukhova, V. Y. Semenov, E. B. Milievskaya [et al.] // Complex Issues of Cardiovascular Diseases. – 2023. – Vol. 12, No. 2. – P. 77–87.
53. Surgical and Interventional Treatment of Patients with Coronary Artery Disease in the Russian Federation (Statistics: 1996–2022) / L. A. Bockeria, V. Y. Semenov, E. B. Milievskaya [et al.] // Thoracic and Cardiovascular Surgery. – 2024. – No. 3. – P. 291–301.
54. Factors associated with surgical site infection in myocardial revascularization: a retrospective longitudinal study / A. G. Pereira, J. M. Lopes, L. S. Pereira [et al.] // Revista Brasileira de Enfermagem. – 2023. – Vol. 76, Suppl 4: e20230108.
55. Current Trends in Coronary Surgery / R. S. Akchurin, A. A. Shiryaev, V. P. Vasilyev [et al.] // Pathology of Blood Circulation and Cardiac Surgery. – 2017. – Vol. 21, No. 3S. – P. 34–44.
56. Bekbolot Uulu Nurboolot. State of Development of Cardiac Surgery Services in Foreign Countries (Literature Review) // Science and Education Issues. – 2024. – No. 8 (180). – P. 19–29.
57. Cardiovascular Surgery – 2022. Diseases and Congenital Anomalies of the Circulatory System / L. A. Bockeria, E. B. Milievskaya, V. V. Pryanishnikov [et al.]. – M.: A.N. Bakulev National Medical Research Center for Cardiovascular Surgery, 2023. – 344 p.
58. Infection of Transcatheter Valvular Devices / T. Hatab, S. Zaid, S. J. Thakkar [et al.] // Current Cardiology Reports. – 2024. – Vol. 26 (7). – P. 767–775.
59. Ali, J. M. Minimally invasive cardiac surgery - a Fad or the Future? / J. M. Ali, Y. Abu-Omar // Journal of Thoracic Disease. – 2021. – Vol. 13 (3). – P. 1882–1885.
60. Results of Cardiac Surgical Interventions in Elderly Patients / P. A. Khazov, A. V. Gurshchenkov, A. D. Maystrenko [et al.] // Cardiology in Belarus. – 2022. – Vol. 14, No. 1. – P. 28–37.
61. An Analysis of 400 Sternal Wound Reconstructions at a Single Institution: Bacterial Pathogens Vary with Time / K. Kuonqui, A. S. Levy, J. R. Tiao [et al.] // Annals of Plastic Surgery. – 2022. – Vol. 88 (3 Suppl 3): S190–S193.
62. Risk Factors Associated with an Increased Risk of Deep Sternal Wound Infections in Patients After Coronary Artery Bypass Grafting and Heart Defect Surgery / M. Vitartaitė, D. Vaičiulytė, J. Venclovienė [et al.] // Heart Surgery Forum. – 2021. – Vol. 24 (4): E741-E745.
63. Cardiovalve in mitral valve position - Additional solution for valve replacement / M. Sherif, S. H. Sündermann, F. Maisano [et al.] // Frontiers in Cardiovascular Medicine. – 2022. – Vol. 9: 960849.
64. Corbisiero, D. The Gallant™ system heart rhythm management device: making a connection / D. Corbisiero, R. Muller // Future Cardiology. – 2022. – Vol. 18 (8). – P. 605–614.
65. Robot-Assisted Repair of Atrial Septal Defect: A Comparison of Beating and Non-Beating Heart Surgery / T. Yun, H. Kim, B. Sohn [et al.] // Journal of Chest Surgery. – 2022. – Vol. 55 (1). – P. 55–60.
66. Regenerative Medicine and Minimally Invasive Technologies in Cardiac Surgery / E. V. Galitsyna, O. S. Kuznetsova, E. A. Kulikova [et al.] // Current Problems of Healthcare and Medical Statistics. – 2023. – No. 4. – P. 164–193.
67. Durko, A. P. Tissue Engineered Materials in Cardiovascular Surgery: The Surgeon's Perspective / A. P. Durko, M. H. Yacoub, J. Kluin // Frontiers in Cardiovascular Medicine. – 2020. – Vol. 7. – P. 55.
68. Mathew, P. Prosthetic Heart Valve. 2023 Jul 24. / P. Mathew, A. Kanmanthareddy // In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. PMID: 30725672.
69. Heart Disease Epidemiology / J. S. Aluru, A. Barsouk, K. Saginala [et al.] // Medical Sciences. – 2022. – Vol. 10. – P. 32.
70. The Society of Thoracic Surgeons Adult Cardiac Surgery Database: 2022 Update on Outcomes and Research / K. M. Kim, A. Arghami, R. Habib [et al.] // The Annals of Thoracic Surgery. – 2023. – Vol. 115 (3). – P. 566–574.
71. Surgical Treatment of Patients with Acquired Heart Valvular Diseases in the Russian Federation (1996–2020) / L. A. Bockeria, E. B. Milievskaya, I. N. Stupakov [et al.] // Thoracic and Cardiovascular Surgery. – 2021. – No. 6. – P. 485–503.
72. Results of Using a Stented Xenopericardial Bioprosthesis in the Aortic Position with the "Easy Change" System, Four-Year Implantation Experience / K. A. Petlin, E. A. Kosovskikh, V. A. Tomilin [et al.] // Siberian Journal of Clinical and Experimental Medicine. – 2021. – Vol. 36, No. 1. – P. 117–122.
73. Composite Chitosan and Polyvinyl Alcohol-Based Biofilms as a Promising Material in Reconstructive Surgery for Infection in Cardiac Surgery. XXIII Annual Session of the A.N. Bakulev National Medical Research Center for Cardiovascular Surgery [Electronic resource]. – URL: https://racvs.ru/events/archive/xxiii_ezhegodnaya_sessiya_nmits_sskh_im_an_bakuleva/kompozitnye_bioplenki_na_osnove_khitozana_i_polivinilovogo_spirta_kak_perspektivnyy_material_v_reko/
74. Application of 3D Printing Technology in Planning Surgical Tactics for Complex Congenital Heart Defects / V. V. Suvorov, V. V. Zaitsev, D. D. Kupatadze [et al.] // Cardiology and Cardiovascular Surgery. – 2020. – Vol. 13, No. 4. – P. 294–298.
75. Clinical Protocol for Surgical and Diagnostic Intervention. Heart Transplantation [Electronic resource]. – URL: https://nephro.kz/images/download/protocols/3_TRANSPLANTATSIYA/12_transplantatsiya_cerdsca.pdf
76. Heart Transplantation Patient Selection. 2024 May 31 / K. N. Brown, J. Abraham, P. T. Ashline [et al.] // In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. PMID: 30725775.
77. Gautier, S. V. Organ Donation and Transplantation in the Russian Federation in 2020. XIII Report of the Register of the Russian Transplant Society / S. V. Gautier, S. M. Khomyakov // Bulletin of Transplantology and Artificial Organs. – 2021. – Vol. 23, No. 3. – P. 8–34.
78. First Experience with Extracorporeal Membrane Oxygenation in Severe Primary Cardiac Allograft Dysfunction / I. V. Abdulyanov, I. M. Rakhimullin, M. R. Gaysin [et al.] // Transplantologiya. – 2020. – No. 12 (4). – P. 301–310.
79. Interhospital variability in health care-associated infections and payments after durable ventricular assist device implant among Medicare beneficiaries / D.S. Likosky, G. Yang, M. Zhang [et al.] // The Journal of Thoracic and Cardiovascular Surgery. – 2022. – Vol. 164 (5). – P. 1561–1568.
80. Huang, Y. H. Health care-associated infections after surgical treatment of ruptured intracranial aneurysms / Y. H. Huang, T. H. Lee // Journal of Stroke and Cerebrovascular Diseases: the official journal of National Stroke Association. – 2024. – Vol. 33 (6): 107725.
81. Racial Health Disparity Associated With Poor Pediatric Cardiac Surgery Outcomes: A Multicentered, Cross-Sectional Study / S. P. Setty, L. C. Reynolds, V. C. Chou [et al.] // JACC. – 2024. – Vol.3 (7): 100987.
82. Epidemiological Characteristics of Healthcare-Associated Infections in Pediatric Cardiac Surgery / A. S. Nabiyeva, B. I. Aslanov, E. M. Shilokhvostova [et al.] // Preventive and Clinical Medicine. – 2022. – No. 3(84). – P. 36–41.
83. Kasatov, A. V. Species Diversity and Biological Properties of Dominant Pathogens of Post-sternotomy Infectious Complications in Cardiac Surgery / A. V. Kasatov, E. S. Gorovits // Perm Medical Journal. – 2020. – Vol. 37, No. 6. – P. 33–41.
84. Nazarchuk, A. A. Microbiological Characteristics of Infectious Complications, Current Aspects of Their Prevention and Treatment in Surgical Patients / A. A. Nazarchuk, M. A. Faustova, S. A. Kolodiy // News of Surgery. – 2019. – Vol. 27 (3). – P. 318–327.
85. Emerging Strategies to Combat ESKAPE Pathogens in the Era of Antimicrobial Resistance: A Review / M. S. Mulani, E. E. Kamble, S. N. Kumkar [et al.] // Frontiers in Microbiology. – 2019. – Vol. 10. – P. 539.
86. Multicomponent Approaches to Reduce Multidrug-Resistant Organisms in Critical Care: Determining the Ideal Strategy / S. AlBahrani, M. Saad, J. S. Alqahtani [et al.] // Journal of Epidemiology and Global Health. – 2024. – Vol. 14 (4). – P. 1371–1380.
87. Risk factors for sternal wound infection after median sternotomy: A nested case-control study and time-to-event analysis / X. Ma, D. Chen, J. Liu [et al.] // International Wound Journal. 2024. – Vol. 21 (7): e14965.
88. The effect of first- and third-generation prophylactic antibiotics on hospitalization and medical expenditures for cardiac surgery / S. J. Bae, I. Kim, J. Song [et al.] // Journal of Cardiovascular Surgery. – 2022. – Vol. 17 (1). – P. 15.
89. Superficial and deep sternal wound infection after more than 9000 coronary artery bypass graft (CABG): incidence, risk factors and mortality / A. Salehi Omran, A. Karimi, S. H. Ahmadi [et al.] // BMC Infectious Diseases. – 2007. – Vol. 7. – P. 112–117.
90. Surgical-site infection after cardiac surgery: incidence, microbiology, and risk factors / D. Lepelletier, S. Perron, P. Bizouarn [et al.] // Infection Control & Hospital Epidemiology. – 2005. – Vol. 26 (5). – P. 466–472.
91. Sharma, M., Sternal surgical-site infection following coronary artery bypass graft: prevalence, microbiology, and complications during a 42-month period / M. Sharma, D. Berriel-Cass, J. Baran // Infection Control & Hospital Epidemiology. – 2004. – Vol. 25 (6). – P. 468–471.
92. Morbidity and mortality of nosocomial infection after cardiovascular surgery: a report of 1606 cases / W. L. Jiang, X. P. Hu, Z. P. Hu [et al.] // Current Medical Sciences. – 2018. – Vol. 38 (2). – P. 329–335.
93. Surgical site infections following coronary artery bypass graft procedures: 10 years of surveillance data / D. Si, M. Rajmokan, P. Lakhan, J. Marquess [et al.] // BMC Infectious Diseases. – 2014. – Vol. 14. – P. 318.
94. Risk factors for ventilator-associated pneumonia due to multi-drug resistant organisms after cardiac surgery in adults / M. Wang, X. Xu, S. Wu [et al.] // BMC Cardiovascular Disorders. – 2022. – Vol. 22 (1). – P. 465.
95. Microbial Contamination after Cardiac Surgery in a Hospital Cardiac Surgery Ward / D. S. Damavandi, M. Javan, H. Moshashaei [et al.] // Journal of Medicine and Life. – 2020. – Vol. 13 (3). – P. 342–348.
96. Mediastinitis in the intensive care unit patient: a narrative review / B. Pastene, N. Cassir, J. Tankel [et al.] // Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases. – 2020. – Vol. 26 (1). – P. 26–34.
97. Laux, C. Staphylococcus aureus Colonization of the Human Nose and Interaction with Other Microbiome Members / C. Laux, A. Peschel, B. Krismer // Microbiology Spectrum. – 2019. – Vol. 7 (2).
98. Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies / S. Blot, E. Ruppé, S. Harbarth, K. Asehnoune [et al.] // Intensive and Critical Care Nursing. – 2022. – Vol. 70: 103227.
99. Nastas, A. T. The socio-economic impact of post cardiac surgery patients with septic-purulent nosocomial infections / A.T. Nastas // Research Journal. – 2018. – Vol. 66. – P. 166–171.
100. Clinical and Epidemiological Features of the Morbidity of Infections Associated with Surgical and Oncological Care / G. G. Badamshina, V. B. Ziatdinov, L. M. Fatkhutdinova [et al.] // Creative Surgery and Oncology. – 2019. – Vol. 9, No. 2. – P. 151–155.
101. Malyshenko, A. A. Active Epidemiological Surveillance as the Key to Effective Infection Prevention in Pediatric Surgery / A. A. Malyshenko, B. I. Aslanov, V. V. Nechaev // Epidemiology and Vaccinal Prevention. – 2018. – No. 17. – P. 76–80.
102. Purulent-Septic Complications of Surgical Pathology of the Mediastinal Organs / A. M. Morozov, V. A. Kadykov, E. M. Askerov [et al.] // Bulletin of the REAVIZ Medical Institute. Rehabilitation, Doctor and Health. – 2023. – Vol. 13 (2). – P. 82–87.
103. Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease / X. Yu, M. Chen, X. Liu [et al.] // BMC Infectious Diseases. – 2020. – Vol. 20 (1). – P. 64.
104. Risk - The Basic Concept of Epidemiology / E. D. Savilov, S. N. Shugaeva, N. I. Briko, S. I. Kolesnikov // Bulletin of the Russian Academy of Medical Sciences. – 2019. – Vol. 74, No. 1. – P. 54–60.
105. Risks of Healthcare-Associated Infections: Problems and Pitfalls / N. I. Shulakova, A. V. Tutelyan, V. V. Maleev, V. G. Akimkin // Health Risk Analysis. – 2023. – No. 2. – P. 104–114.
106. Brusina, E. B. Risk Management of Healthcare-Associated Infections / E. B. Brusina, O. L. Barbarash // Medical Almanac. – 2015. – No. 5 (40). – P. 22–25.
107. Risk Analysis in the Management of a Scientific-Medical Organization / D. V. Kryuchkov, D. V. Karas, Y. V. Danilchenko, A. V. Artamonova // Bulletin of the N.A. Semashko National Research Institute of Public Health. – 2017. – P. 134–138.
108. Burykin, I. M. Risk Management in the Healthcare System as the Basis for the Safety of Medical Care / I. M. Burykin, G. N. Aleeva, R. H. Khafizyanov // Modern Problems of Science and Education. – 2013. – No. 1. – P. 80.
109. Risk Management / Transl. from English. – M.: Alpina Publisher, 2022. – 206 p.
110. Diagnosis and Prevention of Infectious Complications of the Surgical Site / A. M. Morozova, A. N. Sergeev, N. A. Sergeev [et al.] // Bulletin of the Ivanovo Medical Academy. – 2021. – Vol. 26, No. 1. – P. 54–58.
111. Financial Impact of Deep Sternal Wound Infections After Coronary Surgery: A Microcosting Analysis / B. M. M. Orlandi, O. A. V. Mejia, E. M. Trindade [et al.] // Brazilian Journal of Cardiovascular Surgery. – 2023. – Vol. 38 (5): e20220261.
112. Mirkhodzhaev, I. I. Prevention and Surgical Treatment of Sternal Wound Infection After Cardiac Surgery / I. I. Mirkhodzhaev, F. F. Turayev. // New Day in Medicine. – 2020. – No. 4. – P. 60–69.
113. Knowledge, Skills, and Compliance of Nurses Related to Central Line-Associated Bloodstream Infection in the Cardiovascular Department at King Faisal Hospital and Research Centre, Riyadh / V. Perumal, Y. Abdulrhman Alheraish, M. Shahzad [et al.] // Cureus. – 2022. – Vol. 14 (10): e30597.
114. Improving outcomes and reducing costs by modular training in infection control in a resource-limited setting / S. Singh, R. K. Kumar, K. R. Sundaram [et al.] // International Journal for Quality in Health Care. – 2012. – Vol. 24 (6). – P. 641–648.
115. Randomized, multicenter trial comparing sternotomy closure with rigid plate fixation to wire cerclage / K. B. Allen, V. H. Thourani, Y. Naka [et al.] // The Journal of Thoracic and Cardiovascular Surgery. – 2017. – Vol. 153 (4). – P. 888-896.e1.
116. Zhelnina, T. P. Effectiveness of Epidemiological Monitoring in the Prevention of Healthcare-Associated Infections / T. P. Zhelnina, E. B. Brusina // Epidemiology and Vaccinal Prevention. – 2019. No. 3. – P. 84–88.
117. Local Microbiological Monitoring in the Anesthesiology and Intensive Care Departments of the Grodno University Clinic / P. N. Yancevsky, M. V. Ershova, N. N. Chernova, R. V. Yanovich // Journal of the Grodno State Medical University. – 2022. – Vol. 20, No. 1. – P. 73–79.
118. Friedman, N. D. An alternative scoring system to predict risk for surgical site infection complicating coronary artery bypass graft surgery / N. D. Friedman, A. I. Bull, P. I. Russo // Infection Control & Hospital Epidemiology. – 2007. – Vol. 28 (10). – P. 1162–1168.
119. Risk Analysis in the Management of a Scientific-Medical Organization / D. V. Kryuchkov, D. V. Karas, Y. V. Danilchenko, A. V. Artamonova // Bulletin of the N.A. Semashko National Research Institute of Public Health. – 2017. – P. 134–138.
120. Suvorov, V. V. Prevention of Sternal Infection in Cardiac Surgery Patients: abstract of the dissertation ... Candidate of Medical Sciences: 14.01.26 / V. V. Suvorov. – St. Petersburg, 2018. – 26 p.
121. Establishment and Validation of a Nomogram to Predict Hospital-Acquired Infection in Elderly Patients After Cardiac Surgery / Y. Gao, C. Wang, Y. Wang [et al.] // Clinical Interventions in Aging. – 2022. – Vol. 17. – P. 141–150.
122. Risk factors for and incidence of hospital-acquired infections after cardiac surgery in children with congenital heart disease: a single center experience / N. Cındık, M. Gökdemir, M. Çelik [et al.] // Turkish Journal of Pediatrics. – 2023. – Vol. 65. – P. 769–777.
123. The risk factors analysis and establishment of an early warning model for healthcare-associated infections after pediatric cardiac surgery: A STROBE-compliant observational study / L. Meng, J. Li, Y. He [et al.] // Medicine. – 2020. – Vol. 99 (49): e23324.
124. Golubkova, A. A. Features of Purulent-Septic Infections in Patients with Severe Burn Injury / A. A. Golubkova, Y. Y. Kutlakaeva, V. A. Bagin // Epidemiology and Infectious Diseases. – 2021. – No. 5. – P. 214–223.
125. Masud, F. Preventing healthcare-associated infections in cardiac surgical patients as a hallmark of excellence / F. Masud, D. Vykoukal // Methodist DeBakey Cardiovascular Journal. – 2011. – Vol. 7 (2). – P. 48–50.
126. Understanding and Addressing Variation in Health Care-Associated Infections After Durable Ventricular Assist Device Therapy: Protocol for a Mixed Methods Study / P. P. Chandanabhumma, M. D. Fetters, F. D. Pagani [et al.] // JMIR Research Protocols. 2020;9(1):e14701. Published 2020 Jan 7. doi:10.2196/14701
127. Surgical site infections in Eastern Mediterranean region: a systematic review and meta-analysis / A. Maleknejad, D. Nastyar, M. Badakhsh [et al.] // Infectious diseases (London, England). – 2019. – Vol. 51 (10). – P. 719–729.
128. Surgical Site Infections in Cardiac Surgery. Results of Own Research / E. A. Tsoi, L. P. Zuyeva, S. M. Mikayelyan, B. M. Taits // Epidemiology and Vaccinal Prevention. – 2020. – Vol. 9, No. 3. – P. 52–56.
129. Novel Method to Flag Cardiac Implantable Device Infections by Integrating Text Mining With Structured Data in the Veterans Health Administration's Electronic Medical Record / H. J. Mull, K. L. Stolzmann, M. H. Shin [et al.] // JAMA Network Open. – 2020. – Vol. 3 (9): e2012264.
130. Perioperative Antibiotic Prophylaxis in Pediatric Cardiac Surgery-Simple Is Better / J. Burzyńska, R. Jaworski, B. Maruszewski [et al.] // Antibiotics (Basel, Switzerland). – 2022. – Vol. 12 (1). – P. 66.
131. It is time to define an organizational model for the prevention and management of infections along the surgical pathway: a worldwide cross-sectional survey / M. Sartelli, F. M. Labricciosa, F. Coccolini [et al.] // World Journal of Emergency Surgery: WJES. – 2022. – Vol. 17 (1). – P. 17.
132. Strategies for Effective Infection Prevention Programs: Structures, Processes, and Funding / S. Dhar, A. L. Sandhu, A. Valyko [et al.] // Infectious Disease Clinics of North America. – 2021. – Vol. 35 (3). – P. 531–551.
133. Experience of Transitioning to a Risk-Oriented Model of the Quality Management System in a Medical Organization / G. V. Artamonova, D. V. Kryuchkov, E. A. Batsina [et al.] // Healthcare of the Russian Federation. – 2017. No. 6. – P. 309–315.
134. Epidemiological Diagnosis of Infectious Diseases Associated with Healthcare, Based on Standard Case Definitions: Methodological Guide / Association "National Association of Specialists in Control of Infectious and Non-Infectious Diseases" (NASCIB). – M., 2023. – 52 p.
135. WHO Global Priority Pathogens List: A Bibliometric Analysis of Medline-PubMed for Knowledge Mobilization to Infection Prevention and Control Practices in Bahrain / G. V. Asokan, T. Ramadhan, E. Ahmed, H. Sanad // Oman Medical Journal. – 2019. – Vol. 34 (3). – P. 184–193.
136. Development and Application of a System of Standard Operating Procedures in a Medical Organization as a Tool for Ensuring Medical Safety / L. S. Fatkhullina, T. V. Gololobova, O. Y. Alexandrova [et al.] // Problems of Standardization in Healthcare. – 2020. – No. 1-2. – P. 43–51.
137. Methodological Approaches to Implementing a Quality Control System for Medical Care in Medical Organizations / I. A. Zhelenznyakova, Y. V. Seryapina, I. A. Mikhailov [et al.] // Medical Technologies. Assessment and Choice. – 2020. – No. 4 (42). – P. 13–20.
138. Malyshenko, A. A. Risk-Oriented Approach in the Prevention of Surgical Site Infections in Pediatric Surgery / A. A. Malyshenko // Perm Medical Journal. – 2017. – No. 4. – P. 18–23.
139. Epidemiological Diagnostics as the Basis for Risk-Oriented Technologies for Prevention of Nosocomial Infections / L. P. Zuyeva, B. I. Aslanov, K. D. Vasilyev [et al.] // Epidemiology and Vaccinal Prevention. – 2017. – No. 5. – P. 69–73.
140. Kuzmenko, S. A. Risk Factors for Klebsiella pneumoniae Infection in Patients of Pediatric Medical Organizations / S. A. Kuzmenko, M. A. Shmakova, E. B. Brusina // Epidemiology and Vaccinal Prevention. 2020. – No. 2. – P. 40–47.
141. Zakvatova, A. S. Predictive Model for the Development of Bloodstream Infections to Improve Epidemiological Surveillance and Risk-Oriented Prevention Technologies: dissertation ... Candidate of Medical Sciences: 3.2.2. / A. S. Zakvatova. – St. Petersburg, 2022. – 142 p.
142. Kukarkina, V. A. Risk-Oriented Approach to Tuberculosis Prevention in Children Perinatally Exposed to HIV and HIV-Infected Children, and Their Immunization within the National Calendar of Preventive Vaccinations: dissertation ... Candidate of Medical Sciences: 3.2.2. / V. A. Kukarkina. – St. Petersburg, 2022. – 142 p.
143. Malashenko, A. A. Epidemiological Features of Healthcare-Associated Infections in Pediatric Surgery: dissertation ... Candidate of Medical Sciences: 14.02.02 / A. A. Malashenko. – St. Petersburg, 2019. – 156 p.
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For citations:
Sadovnikov E.E. CHARACTERISTICS OF THE EPIDEMIC PROCESS OF HEALTHCARE-ASSOCIATED INFECTIONS IN CARDIAC SURGERY. Complex Issues of Cardiovascular Diseases. 2025;14(6S):273-290. (In Russ.) https://doi.org/10.17802/2306-1278-2025-14-6S-273-290
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